Research Articles
The Two-Faced Protein: How a Cancer-Fighting Discovery Broke the Mold
Discover how synthetic T-cell receptor-like proteins behave as Janus particles in solution, revolutionizing cancer treatment and protein engineering.
Engineering Scissors: How Scientists Are Redesigning Serine Proteases
Explore how scientists are redesigning serine proteases using AI and rational engineering approaches to develop new therapeutics and biotechnology applications.
Engineering Ubiquitin: Reprogramming the Cell's Cleanup Crew to Fight Disease
Discover how scientists are engineering ubiquitin to modulate the ubiquitin-proteasome system, opening new therapeutic possibilities for cancer, neurodegenerative diseases, and more.
Engineering Molecular Scissors: A Revolutionary Approach to Studying Cell Death
Discover how coupled protein and probe engineering enables selective inhibition and labeling of caspases, overcoming long-standing challenges in cell death research.
The Unshakeable Duo: How Two Tiny Amino Acids Shape Life's Energy Machinery
Discover how Asn70 and Pro71 in mitochondrial cytochrome c represent a structural master key essential for life's energy production, revealed through protein engineering.
Forging the Link: How Tethering mRNA to its Protein Supercharges Evolution
Explore how N-terminal mRNA-protein fusion technology is revolutionizing evolutionary protein engineering and accelerating drug discovery.
Shuffle Optimizer: Revolutionizing Protein Engineering Through DNA Shuffling
Discover how Shuffle Optimizer is transforming protein engineering by optimizing DNA shuffling techniques for creating improved enzymes, antibodies, and therapeutic proteins.
Engineering Soluble T-Cell Receptors: The Next Frontier in Cancer Therapy
Explore how scientists are engineering soluble T-cell receptors to create revolutionary cancer therapies that can detect diseases previously invisible to conventional treatments.
Engineering the Unbreakable: The Science Behind Super-Stable Subtilisin BPN'
Explore how protein engineers transform Subtilisin BPN' through strategic mutations to create remarkably thermostable enzymes with industrial and medical applications.
Cellular Conversations: Engineering a New Language Between Proteins
Discover how scientists are engineering novel protein communication networks through membrane-mediated interactions, revolutionizing cellular biology and medical applications.