Research Articles
Anfinsen's Dogma Revisited: The Foundational Principle of Protein Folding and Its Modern Applications in Drug Discovery
This article provides a comprehensive review of Anfinsen's dogma, the central tenet that a protein's amino acid sequence uniquely determines its native three-dimensional structure.
Anfinsen's Dogma Revisited: The Guiding Principle of Protein Folding in Modern Drug Discovery
This article provides a comprehensive exploration of Anfinsen's dogma, the foundational principle that a protein's amino acid sequence uniquely determines its native three-dimensional structure.
From Sequence to Vector: Advanced Amino Acid Tokenization Strategies for Transformers in Drug Discovery
This article provides a comprehensive guide for researchers and drug development professionals on tokenization strategies for amino acid sequences in transformer models.
AlphaFold2 vs. RoseTTAFold: A Head-to-Head Accuracy Comparison for Biomedical Research
This article provides a comprehensive, expert-level comparison of the accuracy, methodology, and practical applications of AlphaFold2 and RoseTTAFold, the two leading AI protein structure prediction tools.
AlphaFold2 vs. ESMFold: A Comprehensive Accuracy Analysis for Protein Structure Prediction in Biomedical Research
This article provides a comparative analysis of AlphaFold2 and ESMFold, the two leading AI-powered tools for protein structure prediction.
AlphaFold2 Validation for Designed Protein Structures: A Practical Guide for Researchers in Drug Discovery
This article provides a comprehensive guide for researchers and drug development professionals on validating computationally designed protein structures using AlphaFold2.
The Complete AlphaFold2 Guide: Step-by-Step Protocol for Accurate Protein Structure Prediction in Biomedical Research
This comprehensive guide provides researchers, scientists, and drug development professionals with a detailed protocol for using AlphaFold2, the groundbreaking AI system for protein structure prediction.
AlphaFold2 vs. ESMFold: The Ultimate Guide to AI Protein Structure Prediction for Drug Discovery
This comprehensive guide explores the revolutionary impact of AlphaFold2 and ESMFold on structural biology and drug development.
AlphaFold vs I-TASSER vs Rosetta: A 2024 Performance Benchmark for Researchers in Structural Biology & Drug Discovery
This article provides a comprehensive, up-to-date comparison of three leading protein structure prediction and modeling tools: AlphaFold (DeepMind), I-TASSER (Zhang Lab), and Rosetta (Baker Lab).
AlphaDesign Framework: The Next Frontier in AI-Driven Generative Protein Design for Therapeutics
This article provides a comprehensive overview of the AlphaDesign framework, a cutting-edge approach for generative protein design.